Table 1. mEPSC characteristics after postsynaptic application of CaMKII inhibitors.
Group (# cells) | RMP (mV) | Frequency (Hz) | Rise time (ms) | Amplitude (pA) | Decay τ (ms) | Conductance (pS) |
---|---|---|---|---|---|---|
CON | ||||||
+sAIP (n=7) | −68.3±1.0 | 0.23±0.03 | 3.6±0.3 | −8.5±0.2 | 19.5±1.6 | 8.6 ±1.0 |
+ AIP (n=6) | −66.0±1.4 | 0.40±0.09 | 2.9±0.2 | −8.6±0.3 | 18.2±1.1 | 10.7±0.9 |
+ACM (n=7) | −65.6±1.9 | 0.30±0.09 | 3.0±0.2 | −8.7±0.2 | 17.8±0.9 | 10.4±0.4 |
FZP | ||||||
+sAIP (n=7) | −64.7±1.4 | 0.35±0.10 | 3.0±0.2 | −9.8±0.2* | 17.0±0.6 | 13.0±1.0** |
+ AIP (n=8) | −67.6±1.9 | 0.37±0.09 | 3.2±0.2 | −8.6±0.4† | 19.5±1.5 | 9.6±0.9 |
+ACM (n=9) | −67.1±2.3 | 0.27±0.03 | 3.2±0.1 | −9.3±0.3 | 17.4±1.4 | 10.8±0.6 |
Values are listed as means±SEM. *p<0.05 (CON+sAIP vs FZP+sAIP); **p<0.01; †p<0.05 (FZP+sAIP vs FZP+AIP).