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. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: Trends Cogn Sci. 2010 May 12;14(7):325–337. doi: 10.1016/j.tics.2010.04.003

Figure 3. How DG and new neurons may affect pattern separation.

Figure 3

Each panel represents how a series of temporally discrete events (left) would be encoded by the hippocampus. (a) Events encoded by the hippocampus without the DG would not be adequately separated, leading to possible clustering of memories based on content. (b) Events encoded by the DG without neurogenesis would be highly separated. (c) Events encoded by the DG with neurogenesis would also be highly separated but would potentially retain their temporal structure. This temporal integration would be provided by the heterogeneous mix of immature neurons.