Table 3.

 Consequences of pooled sensitivity and specificity of faecal calprotectin for patient outcome

Test result	No per 100 patients (prevalence of IBD)		Presumed influence on patient outcome	Importance*
	Adults (32%)	Children and teenagers (61%)
True positive	30	56	Benefit from shorter delay and early treatment	8
True negative	65	30	Benefit from reassurance and avoidance of unnecessary invasive procedure	8
False positive	3	9	Detriment from exposure to invasive procedure; may benefit from endoscopy for correct diagnosis	7
False negative	2	5	Detriment from delayed diagnosis	9
Complications	—	—	Not reliably reported	5
Cost	—	—	No data available	3

IBD=inflammatory bowel disease.

*GRADE recommends classifying patient important outcomes on a 9 point scale: 7-9: critical for decision making; 4-6: important but not critical for decision making; and 1-3: of lower importance to patients.¹⁰⁹