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. Author manuscript; available in PMC: 2010 Jul 16.
Published in final edited form as: Reprod Domest Anim. 2008 Jul;43(Suppl 2):386–392. doi: 10.1111/j.1439-0531.2008.01189.x

Fig. 1.

Fig. 1

Glial cell line-derived neurotrophic factor can signal through activation of Src kinases in SSCs. The GDNF can promote cell cycle progression via activation of Src family kinases (SFKs) such as Src, Yes, Fyn and Lyn. The SFKs further activate a PI3K/Akt pathway, which ultimately leads to an increase in N-myc gene expression (from Braydich-Stolle et al. 2007)