Table 3.
Folding expression of chemokines and receptors in LSK across different locations and stages of development
| Gene | FL14.5 | FL17.5 | FBM17.5 | Adult BM |
|---|---|---|---|---|
| Chemokine (C-C motif) Ligands | ||||
| Ccl4 | 0.02 | 0.17 | 0.18 | 1 |
| Ccl5 | 0.05 | 0.2 | 0.19 | 1 |
| Ccl6 | 0.02 | 0.13 | 0.08 | 1 |
| Ccl9 | 0.09 | 0.24 | 0.18 | 1 |
| Chemokine (C-X-C motif) Ligands | ||||
| Cxcl2 | 0.03 | 0.24 | 0.17 | 1 |
| Pf4 | 0.47 | 0.31 | 1.72 | 1 |
| Chemokine (C-C motif) Receptors | ||||
| Cxcr4 | 0.31 | 0.38 | 0.76 | 1 |
| Other Chemokines and Related Genes | ||||
| Cmtm3 | 0.72 | 0.93 | 0.73 | 1 |
| Cmtm6 | 0.28 | 0.22 | 0.45 | 1 |
| Hif1a | 0.5 | 1.07 | 0.75 | 1 |
| Il16 | 0.42 | 0.37 | 0.82 | 1 |
| Il18 | 0.04 | 0.21 | 0.57 | 1 |
| Mmp2 | 0.07 | 0.2 | 0.27 | 1 |
| Nfkb1 | 0.48 | 0.82 | 0.84 | 1 |
| Tlr4 | 0.01 | 0.11 | 0.23 | 1 |
| Tnfrsf1a | 0.4 | 0.45 | 0.71 | 1 |
| Tnfsf14 | 0.18 | 0.31 | 0.43 | 1 |
| Housekeeping Gene | ||||
| Hprt1 | 0.48 | 0.81 | 0.63 | 1 |
This table demonstrates fold change values for samples in which gene expression was detected at all the points of study, compared to gene expression in adult bone marrow. Adult BM, four-week old adult bone marrow; FBM17.5, fetal bone marrow at Day 17.5 of gestation; FL14.5, fetal liver at Day 14.5 of gestation; FL17.5, fetal liver at Day 17.5 of gestation; LSK, Lineage- Sca-1+ c-Kit+.