. Author manuscript; available in PMC: 2010 Jul 16.

Published in final edited form as: Obesity (Silver Spring). 2009 Apr 16;17(10):1821–1829. doi: 10.1038/oby.2009.107

Table 3.

Summary of results for primary analysis of metabolic parameters with and without adjustment for body-weight (wt) loss, mean (s.e.m.)

Parameter	Overall treatment effect, β1	Effect independent of wt loss, β	%Overall effect not explained by wt, β/β1 (%)
HDL-C (%)	8.0 (0.6)	3.6 (0.6)	45
	P < 0.001	P < 0.001
Triglycerides (%)	−14.0 (1.4)	−6.5 (1.4)	46
	P < 0.001	P < 0.001
HbA_1c (%)	−0.67 (0.007)	−0.37 (0.007)	55
	P < 0.001	P < 0.001
Fasting insulin (μU/ml)	−2.74 (0.48)	−1.34 (0.51)	49
	P < 0.001	P = 0.018
Adiponectin (μg/ml)	1.5 (0.2)	0.85 (0.21)	57
	P < 0.001	P < 0.001

HDL-C, high-density lipoprotein-cholesterol.

Data from ref. 83.