Figure 2.
Effects of lidocaine (100 μg) inactivation of the lateral dorsal striatum (left panels) and lateral orbitofrontal cortex (right panels) on the dose-related effects of self-administered cocaine (x-axis, log scale) for the entire 1-hr test sessions. Values are the mean ± S.E.M. number of active and inactive lever responses (top panels) and infusions earned (bottom panels). * p ≤ 0.05 compared to the corresponding cocaine dose after vehicle treatment or the no-treatment control condition. See text for specific probability values associated with each comparison.