Table 2.
Regional theta activity showing significant group differences (Healthy controls minus Depressed patients) during navigation on hidden and visible platform trials
| Local maximum | ||||||||
|---|---|---|---|---|---|---|---|---|
| Region | BA | Time (s) | Side | Size | x | y | z | Student t |
| Hidden condition | ||||||||
| Anterior cingulate | 32 | 0.50-1.50 | L | 5 | –17 | +38 | +7 | +4.14 |
| 32 | 2.25-3.25 | L | 3 | –17 | +43 | –8 | +3.36 | |
| Cerebellum | – | 3.75-4.75 | L | 18 | –2 | –57 | –23 | –4.08 |
| Cingulate | 31 | 2.25-3.25 | L | 2 | –17 | –22 | +42 | +3.11 |
| 31 | 4.00-5.00 | L | 39 | –2 | –42 | +42 | +3.50 | |
| Hippocampus | – | 1.25-2.25 | R | 4 | +33 | –22 | –8 | +3.48 |
| – | 3.25-4.25 | R | 16 | +33 | –17 | –13 | +3.77 | |
| Inferior frontal | 47 | 1.00-2.00 | R | 5 | +43 | +28 | –18 | +3.05 |
| 46 | 1.75-2.75 | L | 2 | –42 | +43 | +7 | +2.91 | |
| 47 | 3.00-4.00 | L | 4 | –52 | +38 | –13 | +3.41 | |
| 45 | 3.25-4.25 | R | 15 | +53 | +33 | +2 | +4.67 | |
| 47 | 3.50-4.50 | R | 6 | +48 | +33 | –3 | +4.16 | |
| 47 | 3.75-4.75 | R | 2 | +48 | +28 | –3 | +2.61 | |
| 47 | 3.75-4.75 | L | 6 | –42 | +13 | –3 | –2.96 | |
| Inferior parietal | 40 | 3.25-4.25 | R | 2 | +63 | –22 | +22 | +2.73 |
| Lingual | 19 | 2.00-3.00 | R | 3 | +23 | –57 | –3 | –3.05 |
| Middle frontal | 46 | 0.50-1.50 | R | 14 | +38 | +43 | +7 | +3.65 |
| 9 | 1.50-2.50 | L | 2 | –42 | +33 | +32 | +2.52 | |
| 46 | 2.00-3.00 | R | 7 | +48 | +43 | +27 | +5.64 | |
| 10 | 2.50-3.50 | R | 7 | +33 | +63 | +2 | +4.68 | |
| 10/11 | 3.50-4.50 | L | 35 | –27 | +48 | –8 | +4.07 | |
| 10 | 3.75-4.75 | L | 5 | –32 | +53 | –3 | +3.94 | |
| 10 | 4.00-5.00 | L | 6 | –37 | +48 | +7 | +3.13 | |
| Middle occipital | 18 | 0.00-1.00 | R | 2 | +38 | -87 | +2 | –2.83 |
| Middle temporal | 21 | 0.00-1.00 | L | 2 | –67 | –32 | +2 | +3.14 |
| 21 | 2.00-3.00 | R | 5 | +53 | +8 | –33 | +3.92 | |
| 21 | 2.00-3.00 | R | 2 | +63 | +3 | –18 | +3.87 | |
| Parahippocampal | 34 | 0.75-1.75 | R | 4 | +17 | +2 | –13 | +2.79 |
| Parahippocampal | 28/34 | 2.75-3.75 | R | 3 | +18 | –7 | –13 | +4.17 |
| 28/34 | 3.00-4.00 | R | 3 | +18 | –7 | –13 | +3.97 | |
| Posterior cingulate | 31 | 0.50-1.50 | L | 3 | –7 | –62 | +17 | –3.42 |
| Precentral | 4 | 2.25-3.25 | L | 2 | –27 | –17 | +47 | +3.31 |
| Superior frontal | 10 | 1.75-2.75 | R | 11 | +3 | +68 | +22 | +5.24 |
| 11 | 1.75-2.75 | R | 7 | +13 | +48 | –13 | +3.56 | |
| 8 | 1.75-2.75 | R | 7 | +38 | +23 | +52 | +5.92 | |
| 11 | 2.00-3.00 | L | 2 | –22 | +63 | –13 | +4.51 | |
| 46 | 2.25-3.25 | R | 5 | +48 | +43 | +32 | +4.64 | |
| 10 | 2.75-3.75 | L | 3 | –27 | +58 | –3 | +3.04 | |
| 11 | 3.25-4.25 | L | 16 | –22 | +43 | –3 | +4.17 | |
| Superior parietal | 7 | 4.00-5.00 | R | 2 | +28 | –62 | +52 | –3.00 |
| Superior temporal | 38 | 4.00-5.00 | R | 13 | +53 | +13 | –28 | +4.11 |
| Supramarginal | 40 | 4.00-5.00 | R | 2 | +58 | –47 | +32 | –2.73 |
| Visible Condition | ||||||||
| Cerebellum | – | 2.75-3.75 | R | 15 | +28 | –62 | –18 | –2.86 |
| – | 3.25-4.25 | R | 2 | +33 | –52 | –18 | –2.60 | |
| Cuneus | 7 | 0.25-1.25 | L | 4 | –17 | –72 | +32 | –3.81 |
| 18/19 | 1.75-2.75 | L | 3 | –17 | –87 | +22 | –3.17 | |
| 19 | 1.75-2.75 | L | 2 | –7 | –92 | +27 | –5.06 | |
| 18/19 | 2.75-3.75 | L | 16 | –12 | –82 | +27 | –3.66 | |
| 18 | 3.00-4.00 | L | 21 | -17 | –77 | +22 | –3.80 | |
| 18 | 3.75-4.75 | L | 11 | +8 | –77 | +22 | –3.67 | |
| Medial frontal | 6 | 1.50-2.50 | L | 2 | –7 | –7 | +57 | –2.79 |
| Middle frontal | 47 | 0.25-1.25 | L | 2 | –32 | +38 | –3 | –2.96 |
| Paracentral | 6 | 0.00-1.00 | L | 3 | –12 | –27 | +52 | –3.08 |
| 3/4 | 0.25-1.25 | L | 2 | –12 | –37 | +57 | –4.12 | |
| 5 | 2.75-3.75 | L | 13 | –17 | –42 | +57 | –3.92 | |
| Parahippocampal | 35 | 1.75-2.75 | L | 3 | –17 | –32 | –8 | +3.41 |
| Postcentral | 5 | 0.25-1.25 | L | 2 | –12 | –42 | +62 | –3.81 |
| 3 | 0.50-1.50 | L | 9 | –12 | –37 | +67 | –3.77 | |
| Precuneus | 7 | 2.50-3.50 | L | 24 | –22 | –62 | +37 | –4.05 |
| Superior frontal | 6/8 | 3.25-4.25 | L | 3 | –17 | +28 | +52 | +4.08 |
| 6/8 | 3.75-4.75 | R | 4 | +13 | +33 | +52 | +3.93 | |
| Superior temporal | 22 | 2.50-3.50 | L | 2 | –62 | –52 | +12 | +3.04 |
Note: Size refers to the number of contiguous voxels (5mm3) surviving multiple comparison correction (i.e., false discovery rate < 5%). Coordinates of local maxima are in mm units and correspond to standardized Talairach space. BA = Brodmann Area.