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. 2010 Jun 8;103(1):52–60. doi: 10.1038/sj.bjc.6605727

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Copyright © 2010 Cancer Research UK

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(A) Representative K^trans maps of PaCa13 tumours after treatment with vehicle control (0.9% saline), maximum tolerated dose gemcitabine (MTD Gem; 240 mg kg⁻¹ on days 1, 8, and 15), or metronomic gemcitabine (30 mg kg⁻¹, q3d) for 4 weeks. (B) Effects of different treatments on median values of K^trans in viable tumour tissues in PaCa8 and PaCa13 tumours. Each symbol represents an evaluable tumour from a mouse in the corresponding group. —, mean; bars, s.e. ^*P<0.05, significantly different from that of vehicle control. ^#P<0.05, significantly different from that of MTD gemcitabine.