Table 4. Hazard ratio for breast cancer risk in relation to level of serum GGT (adjusted by age, age at first birth/nulliparity, age at menarche, height and weight).
All
|
||
---|---|---|
HR (95% CI) | P-value | |
N (cases) | 1803 (96) | |
GGT in quartiles | ||
Q1 (⩽8.0 IU l−1) | 1.00 | 0.011 |
Q2 (8.1–11.0 IU l−1) | 1.55 (0.81, 2.97) | |
Q3 (11.1–14.0 IU l−1) | 2.41 (1.33, 4.35) | |
Q4 (>14.0 IU l−1) | 2.17 (1.19, 3.93) | |
GGT by median value | ||
Below median (11.0 IU l−1) | 1.00 | 0.004 |
Above median | 1.88 (1.23, 2.87) | |
GGT by normal range | ||
In normal range (⩽40 IU l−1) | 1.00 | 0.003 |
Above normal range | 2.50 (1.36, 4.60) |
Abbreviation: CI=confidence interval; HR=hazard ratio; GGT=γ-glutamyl transferase; Q1, first quartile; Q2, second quartile; Q3, third quartile; Q4, fourth quartile. Values in bold type represent significant P-values (P<0.05)