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. 2010 Jun 1;103(1):36–42. doi: 10.1038/sj.bjc.6605713

Figure 1.

Figure 1

Effect of YM155 on survivin expression in human non-small cell lung cancer (NSCLC) cells. (A) H460, Calu6, H358, or PC14 cells were incubated in the absence (control, 0.1% dimethyl sulfoxide (DMSO)) or presence of the indicated concentrations of YM155 for 48 h. Cell lysates were then prepared and subjected to immunoblot analysis with antibodies to survivin or to β-actin (loading control). (B) H460, Calu6, H358, or PC14 cells were incubated in the absence or presence of 50 nM YM155 for 48 h, after which cell lysates were subjected to immunoblot analysis with antibodies to survivin, c-IAP1, XIAP, or β-actin.