Fig. 3.

Amino acid sequences that define the most commonly observed α- and β-chain isoHbs in deer mice from Colorado. (A) Seven allelic α-globin variants defined by different 8-site amino acid combinations. In the sample of highland mice, the most common allele at the HBA-T1 and HBA-T2 genes matched the α^I sequence, and in the sample of lowland mice, the most common allele at these same genes matched the α^VII sequence. (B) Three allelic β-globin variants defined by different 4-site amino acid combinations. In the sample of highland mice, the most common allele at the HBB-T1 and HBB-T2 genes matched the β^I sequence, and in the sample of lowland mice, the most common allele at these same genes matched the β^III sequence. Shading denotes the amino acid variants that predominate in the lowland population.