Table 3.
Significant haplotypes of markers at the ITGA11 gene region associated with tick burden
| SNP1 | Code | Sample2 | N03 | N1 | N2 | R2 4 | α5 | SE6 | p-value |
|---|---|---|---|---|---|---|---|---|---|
| 10snp h10 |
110111111 - 0 | DTE (48) |
605 | 17 | 0 | 0.0146 | -0.738 | 0.243 | 0.0025 |
| 10snp h19 |
111000111 - 0 | DTE (48) |
582 | 38 | 2 | 0.0131 | -0.432 | 0.151 | 0.0043 |
| 10snp h23 |
111010101 - 0 | BRM (24) |
419 | 4 | 0 | 0.0422 | 2.119 | 0.492 | 2 × 10-5^ |
| 4,5,6 h7 |
- - - 010 - - - - - | DTE (8) |
808 | 23 | 1 | 0.0082 | -0.507 | 0.194 | 0.0092 |
| BRM (5) |
477 | 8 | 0 | 0.0386 | 1.542 | 0.350 | 1 × 10-5^ | ||
| 6,7,8 h1 |
- - - - - 001 - - - | DTE (7) |
891 | 124 | 10 | 0.0125 | -0.297 | 0.083 | 0.0003^ |
| 7,8,9 h2 |
- - - - - - 011 - - | DTE (7) |
734 | 156 | 0 | 0.0077 | -0.231 | 0.088 | 0.0087 |
| 7,8,9 h7 |
- - - - - - 101 - - | BRM (5) |
476 | 42 | 2 | 0.0128 | 0.380 | 0.147 | 0.0099^ |
| 8,9,10 h2 |
- - - - - - - 011 - | BRM (3) |
477 | 42 | 2 | 0.0128 | 0.381 | 0.147 | 0.0097^ |
| 8,9,10 h5 |
- - - - - - - 111 - | BRM (3) |
6 | 98 | 417 | 0.0183 | -0.310 | 0.100 | 0.0020^ |
| 8,9,11 h2 |
- - - - - - - 10 - 1 | BRM (5) |
513 | 5 | 0 | 0.0261 | 1.651 | 0.444 | 0.0002^ |
| 8,9,11 h3 |
- - - - - - - 11 - 0 | DTE (6) |
538 | 332 | 8 | 0.0117 | -0.212 | 0.066 | 0.0013^ |
| BRM (5) |
8 | 102 | 408 | 0.0150 | -0.269 | 0.096 | 0.0053^ | ||
| 9,10,11 h2 |
- - - - - - - - 011 | BRM (5) |
537 | 5 | 0 | 0.0233 | 1.596 | 0.444 | 0.0004^ |
1 SNP markers used to generate the haplotypes (4- rs29025981, 5- rs41594962, 6- ss161109814, 7- ss161109807, 8- ss161109797, 9- rs29023635, 10- rs29023639, 11- rs29014770) and haplotype number.
2 DTE - dairy tick experiment, BRM - Brahman and number of haplotypes reconstructed.
3 N0 number of animals with zero copies of the haplotype, N1 number of animals with one copy of the haplotype, N2 number of animals with two copies of the haplotype.
4 Proportion of residual variance explained by the common haplotype.
5 Haplotype substitution effect in phenotypic standard deviations (tick count for the DTE and tick score for BRM).
6 Standard error of α.
^ Significant after Bonferroni correction.