Table 4.

Main topological parameters and the most connected nodes of C∩A network

	C∩A
N°nodes	109
N°edges	143
Clustering coefficient	0.036
Diameter	20
Averaged n°neighbours	2.606
Char. path length	6.957
IN degree distribution	b = -1.829
	r = 0.997 R2 = 0.948
OUT degree distribution	b = -2.240 r = 0.992 R2 = 0.894
Hub (n°edges)	ATP (13); Ca2+ (12)

The number of nodes represent the total number of molecules involved, the number of edges represents the total number of interaction found, the clustering coefficient is calculated as CI = 2nI/k(k-1), where nI is the number of links connecting the kI neighbours of node I to each other, the network diameter is the largest distance between two nodes, the Averaged n°neighbours represent the mean number of connection of each node, the Char. path length gives the expected distance between two connected nodes.