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. 2010 Jul 16;5(7):e11619. doi: 10.1371/journal.pone.0011619

Figure 3. dSno cannot rescue constitutively active Notch.

Figure 3

(A) MS1096.Gal4; Ac-lacZ disk labeled with anti-lacZ to display Ac expression (green) and anti-Cut (red). Expression in three rows of cells either adjacent to (Ac) or on (Cut) the wing margin that will become bristles in the adult wing is visible with Ac only present in cells of the anterior compartment (arrowhead). (B) MS1096.Gal4; UAS.dSno, Ac-lacZ disk has reduced Ac-lacZ expression but largely normal Cut expression. (C) MS1096.Gal4; UAS.CA-Notch, Ac-lacZ disk has no Ac-lacZ expression but nearly ubiquitous expression of Cut. (D) MS1096.Gal4; UAS.dSno, UAS.CA-Notch, Ac-lacZ disk is qualitatively the same as UAS.CA-Notch alone.