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. 2010 Jul 16;5(7):e11619. doi: 10.1371/journal.pone.0011619

Figure 4. dSno cannot rescue dominant negative Notch or Mastermind.

Figure 4

(A) MS1096.Gal4; UAS.DN-Notch wing is small, has no veins and very few anterior margin bristles. (B) MS1096.Gal4; UAS.MamN wing is smaller than wild type but modestly larger than the UAS.DN-Notch wing, has vein defects and gaps in the anterior margin bristles. (C) MS1096.Gal4; UAS.DN-Notch disk labeled with anti-Ac (green) and anti-Sens (red). Expression in cells adjacent to the wing margin is indicated (arrowhead). The disk has reduced Ac and Sens expression compared to the wild type disk in Fig. 2C. (D) MS1096.Gal4; UAS.MamN disk has approximately wild type Ac and Sens expression. (E) MS1096.Gal4; UAS.dSno, UAS.DN-Notch wing is smaller than UAS.DN-Notch alone, is veinless and has no margin bristles. (F) MS1096.Gal4; UAS.dSno, UAS.MamN wing is smaller than UAS.MamN alone, is veinless and the anterior margin bristles are completely disorganized (G) MS1096.Gal4; UAS.dSno, UAS.N-Notch disk has less Ac and Sens expression than UAS.DN-Notch alone. (H) MS1096.Gal4; UAS.dSno, UAS.MamN disk has less Sens and Ac expression then UAS.MamN alone.