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. 2010 Jul 16;5(7):e11629. doi: 10.1371/journal.pone.0011629

Figure 6. The expression of proteins involved in iron transport in SK-Mel-5 cells indicates a decrease in iron stores.

Figure 6

The expression of transferrin receptor 1, ferritin and ferroportin in HeLa and SK-Mel-5 cells in the presence or absence of DFO was measured by immunoblotting. Relative to HeLa cells, SK-Mel-5 have decreased expression of transferrin receptor and ferritin and a large increase in expression of the iron efflux protein ferroportin. TfR, transferrin receptor. DMT1, divalent metal transporter 1. FPN1, ferroportin 1. FTH, ferritin H heavy chain. The immunoblots shown are representative of two independent experiments.