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. 2010 Feb 16;132(7):074101. doi: 10.1063/1.3310809

Figure 1.

Figure 1

Projection error (ϵ) for varying number of molecules given τD=0.1 s, ℓ=0.62 μm, and D=0.001 μm2 s−1. Adaptive step splitting allows us to take advantage of the independence of diffusing molecules and the nonlinear relationship of projection error to the number of molecules diffused to reduce the total error of diffusion step over τD by splitting it into sub-subproblems of fewer molecules rather than by splitting the time step.