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. Author manuscript; available in PMC: 2011 Jul 14.
Published in final edited form as: J Am Chem Soc. 2010 Jul 14;132(27):9265–9267. doi: 10.1021/ja103043p

Figure 1.

Figure 1

The reaction scheme showing binding of a target DNA to the surface-bound probe DNA with a 5´ overhang. This overhang is used as a template for Klenow Fragment DNA polymerase. The slide is then heated and SPRI is used to detect the binding of a complementary DNA-associated gold nanoparticle.