Table 2.
Characteristics at baseline and BP responses to sodium intervention for all study participants
| Probands | Siblings | Spouses | Offspring | Parents | |
|---|---|---|---|---|---|
| No. of subjects | 676 | 956 | 69 | 205 | 1236 |
| Age, yrs | 41.0 ± 8.3 | 39.6 ± 7.7 | 49.1 ± 6.7 | 23.5 ± 6.5 | 67.6 ± 8.4 |
| Male, % | 60.4 | 51.1 | 33.3 | 44.4 | 48.6 |
| Body mass index, kg/m2 | 24.2 ± 3.3 | 23.1 ± 2.8 | 23.4 ± 3.7 | 21.5 ± 3.3 | 22.8 ± 3.4 |
| BP at baseline, mm Hg | |||||
| Systolic | 128.0 ± 11.4 | 111.6 ± 11.5 | 112.6 ± 14.9 | 106.6 ± 10.3 | 136.6 ± 23.9 |
| Diastolic | 80.3 ± 9.0 | 71.0 ± 8.9 | 72.6 ± 10.0 | 65.3 ± 9.0 | 75.0 ± 11.7 |
| Mean arterial pressure | 96.7 ± 8.5 | 84.5 ± 9.2 | 85.9 ± 11.2 | 79.1 ± 8.7 | 95.6 ± 14.3 |
| BP response to low salt, % | |||||
| Systolic | −6.1 ± 6.0 | −3.7 ± 5.0 | −4.4 ± 5.8 | −2.0 ± 4.5 | – |
| Diastolic | −5.1 ± 7.2 | −2.4 ± 7.4 | −3.4 ± 6.8 | −2.4 ± 8.1 | – |
| Mean arterial pressure | −5.6 ± 5.8 | −3.0 ± 5.5 | −3.8 ± 5.8 | −2.3 ± 5.5 | – |
| BP response to high salt, % | |||||
| Systolic | 4.9 ± 5.6 | 4.4 ± 5.5 | 5.4 ± 5.5 | 2.5 ± 4.2 | – |
| Diastolic | 3.6 ± 8.1 | 2.8 ± 7.7 | 2.9 ± 6.5 | 1.7 ± 8.5 | – |
| Mean arterial pressure | 4.1 ± 6.2 | 3.4 ± 6.0 | 3.9 ± 5.4 | 2.0 ± 5.3 | – |
Continuous variables are indicated as mean ± standard deviation. BP, blood pressure.