Table 1. Subject Demographics, Cognitive Measures, STS Volumes, Reaction Times, Number of Correct Responses.
+ Chi Square distribution was performed on gender distribution. Subjects were one-to-one matched on age and group matched on PSES, years of education and IQ. The SPD subjects had smaller left STS volumes in the lower bank and total STS at the trend level compared with HC. There was no difference between groups in reaction time on the prosody identification fMRI task. SPD subjects had more difficulty than did HC subjects identifying sad emotion at the trend level in an exploratory analysis (Fig 5b).
| (N=SPD, HC) | SPD | CONTROL | F, | P | ||
|---|---|---|---|---|---|---|
| Subject Demographics | ||||||
| Gender + | male=13, | female=3 | male=9, | female=4 | .566, | <0.5 |
| Age (16, 13) | 39.1 | (11.0) | 35.2 | (12.3) | .925, | 0.3 |
| PSES (16, 12) | 3.6 | (1.2) | 3.7 | (1.2) | .053, | 0.8 |
| SES (15, 11) | 3.2 | (1.0) | 3.8 | (.8) | 2.905 | 0.1 |
| Education (16, 13) | 14.7 | (2.1) | 15.1 | (1.6) | .287, | 0.6 |
| Vocabulary (IQ) (16, 13) |
11.9 | (4.4) | 13.1 | (3.2) | .675, | .4 |
| Cognitive Measures | ||||||
| Verbal Fluency “c” (129,138) |
14.9 | (4.6) | 16.5 | (4.0) | 8.466 | 0.004 |
| Verbal Fluency “animals” (124,131) |
24.2 | (6.1) | 27.5 | (5.7) | 14.201, | <0.0005 |
| SSPT total correct (67,73) |
55.7 | (2.8) | 56.6 | (2.2) | 4.307 | 0.04 |
| STS Volumes (absolute volumes in mls) (SPD=30, NC=30) | ||||||
| Left Upper STS | 3.5 | (1.0) | 3.7 | (1.0) | 2.069 | <0.2 |
| Left Lower STS | 3.3 | (1.0) | 3.6 | (.8) | 3.932 | 0.052 |
| Total Left STS | 6.8 | (1.8) | 7.4 | (1.7) | 3.454 | <0.07 |
| Right Upper STS | 4.2 | (1.3) | 4.3 | (1.1) | .321 | <0.6 |
| Right Lower STS | 4.1 | (1.3) | 4.1 | (1.1) | .011 | 0.9 |
| Total Right STS | 8.4 | (2.5) | 8.4 | (2.2) | .118 | 0.7 |
| Reaction Time (in seconds) | ||||||
| Time: Happy (16/14) |
2.5 | (.3) | 2.5 | (.2) | .054, | 0.8 |
| Time: Sad (16/14) | 2.8 | (.2) | 2.7 | (.1) | .487, | <0.5 |
| Time: Sarcastic (16/14) |
3.1 | (.1) | 3.0 | (.1) | .666, | 0.4 |
| Time: Neutral (15/14) |
2.8 | (.2) | 2.7 | (.2) | .155, | <0.7 |
| Time: Total (15/14) | 11.1 | (.7) | 10.9 | (.4) | .153, | <0.7 |
| Number of Correct Responses | ||||||
| Correct: Happy (16/14) |
35.4 | (11.2) 71% | 40.5 | (6.9) 81% | 2.023, | <0.2 |
| Correct: Sad (16/14) |
37.06 | (9.7) 74% | 42.7 | (4.2) 85% | 3.804, | 0.06 |
| Correct: Sarcastic (16/14) |
29.0 | (10.7) 58% | 30.9 | (7.3) 61% | .279 | 0.6 |
| Correct: Neutral (15/13) |
37.9 | (9.7) 76% | 40.7 | (6.9) 81% | 1.108, | 0.3 |
| Correct: Total (15/13) |
139.4 | (32.8) 70% | 154.8 | (19.6) 77% | 2.057, | <0.2 |