Table 2. Exploratory whole-brain analysis across conditions, uncorrected p = 0.001, one-sample t tests.

HC subjects demonstrated a peak in the hemodynamic response curve in the left STS and left insula, not seen in SPD subjects. Note that the SPD subjects activated additional frontal and left hippocampal regions not seen in HC subjects (Fig 10). These analyses were for exploratory purposes only.

Region	Cluster size	T	P (uncorrected)	x	y	z
Healthy control subjects
Temporal lobe
Right STG	1541	6.84	<0.0005	64	−20	−8
Left STG	1207	6.37	<0.0005	−50	−26	−2
Left STS	15	4.29	0.001	−52	−44	14
Parietal lobe
Right superior parietal gyrus	11	6.19	<0.0005	24	−74	58
Frontal lobe
Left inferior frontal gyrus	159	4.71	<0.0005	−46	16	26
Right superior frontal gyrus	154	4.91	<0.0005	10	6	62
Insula
Left short insular gyrus	46	4.83	<0.0005	−34	26	2
SPD subjects
Temporal lobe
Right STG	1756	10.95	<0.0005	56	−40	4
Left STG	2871	10.25	<0.0005	−52	−10	4
Left parahippocampus	13	4.45	<0.0005	−18	−26	−20
Frontal lobe
Left middle frontal gyrus	2071	10.38	<0.0005	−46	−6	52
Left superior frontal gyrus	691	8.17	<0.0005	−2	−4	66
Right precentral gyrus	665	7.29	<0.0005	56	4	28
Right precentral gyrus	139	5.50	<0.0005	42	−6	46
Right precentral gyrus	247	5.42	<0.0005	38	−20	60
Left inferior frontal gyrus	338	6.09	<0.0005	−38	30	−4