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. Author manuscript; available in PMC: 2010 Jul 17.
Published in final edited form as: Biochem Biophys Res Commun. 2005 Aug 5;333(3):1026–1033. doi: 10.1016/j.bbrc.2005.05.191

Figure 3.

Figure 3

Manassantins and 4-O-methylsaucerneol block the induction of secreted VEGF proteins (VEGF121 and VEGF165) by hypoxia in T47D cells. Following compound treatment under hypoxic conditions (1% O2) for 16 h, levels of secreted VEGF proteins in the conditioned media were determined by ELISA and normalized to the number of viable cells. The control "C" represents media only. Data shown are mean ± SE from one representative experiment performed in triplicate. An asterisk (*) indicates p <0.05 when compared to the normoxic control. The p values between the hypoxic control and the compound treatments are indicated.