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. 2010 Apr;62(4):1007–1016. doi: 10.1002/art.27346

Figure 3.

Figure 3

Binding of 1-11E to cartilage from mice with experimental inflammatory arthritis and posttraumatic osteoarthritis (OA). A and B, Inflamed cartilage was uniformly and strongly stained with 1-11E (A), while no staining was observed using irrelevant anti–hen egg lysozyme (anti-HEL) single-chain variable fragment (scFv) (B). C, Antibody 1-11E did not stain control uninflamed cartilage. D, Strong pericellular staining with 1-11E was observed in the damaged area of cartilage from mice with knee injury that developed posttraumatic OA. E, No binding was observed using control anti-HEL scFv. Bars = 100 μm.