Table 1.
Method | Tmaxthresh | CBF (ml/100 g/min) | CBF Ratio | COV |
---|---|---|---|---|
xeCT (gold-standard) | – | 35.8 ± 7.7 | – | |
DSC | – | 14.6 ± 6.3* | 0.43 ± 0.21 | 47% |
ASL | – | 31.4 ± 9.9 | 0.91 ± 0.31 | 34% |
CAD-CBF | 2 sec | 29.0 ± 10.1 | 0.83 ± 0.29 | 35% |
3 sec | 31.2 ± 9.8 | 0.90 ± 0.30 | 33% | |
4 sec | 32.0 ± 10.1 | 0.93 ± 0.32 | 34% | |
5 sec | 32.0 ± 10.0 | 0.93 ± 0.31 | 33% | |
6 sec | 31.8 ± 10.0 | 0.92 ± 0.31 | 32% | |
∞ | 31.4 ± 9.9 | 0.92 ± 0.31 | 32% | |
DSC scaled by white matter ROI of 22 mL/100 g/min | 43.4 ± 7.4 | 1.29 ± 0.46 | 36% |
All values mean ± standard deviation. Tmaxthresh: Tmax threshold for including voxel in the calculation of the correction factor. CBF ratio = mean MR-based CBF value divided by the mean xeCT CBF value (i.e., for no bias, CBF ratio = 1.0). COV = SD normalized by the mean (for perfect precision, COV = 0%).
Significantly different from xeCT CBF (P < 0.01, paired t test).