Table 1.
A | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
All Clones | DAL | DAM | BA | BLA | BLD | DPL | DPM | CP | MB | BLV | |
Total clones | 134 | 13 | 1 | 16 | 22 | 13 | 29 | 5 | 8 | 12 | 10 |
Abnormal clones | 43 | 5 | 0 | 2 | 8 | 3 | 13 | 4 | 3 | 2 | 2 |
Percent of Total | 32% | 38% | 0% | 13% | 36% | 23% | 45% | 80% | 38% | 17% | 20% |
p-value | n/a | 0.210 | 0.681 | 0.066 | 0.175 | 0.209 | 0.072 | 0.041 | 0.277 | 0.154 | 0.221 |
B | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
DAL | ||||||||||
DAM | 0.643 | |||||||||
BA | 0.099 | 0.882 | ||||||||
BLA | 0.279 | 0.652 | 0.081 | |||||||
BLD | 0.236 | 0.786 | 0.289 | 0.219 | ||||||
DPL | 0.247 | 0.567 | 0.023 | 0.189 | 0.117 | |||||
DPM | 0.132 | 0.333 | 0.011 | 0.092 | 0.045 | 0.145 | ||||
CP | 0.354 | 0.667 | 0.158 | 0.328 | 0.295 | 0.295 | 0.163 | |||
MB | 0.176 | 0.846 | 0.387 | 0.161 | 0.355 | 0.071 | 0.027 | 0.238 | ||
BLV | 0.236 | 0.818 | 0.361 | 0.223 | 0.382 | 0.121 | 0.045 | 0.294 | 0.406 | |
DAL | DAM | BA | BLA | BLD | DPL | DPM | CP | MB | BLV |
Calculations were carried out using “Simple Interactive Statistical Analysis” available at http://www.quantitativeskills.com/sisa/statistics/t-thlp.htm. Because the data set contained values close to or equal to 0, Fisher exact analysis was used for all comparisons. Design effects were set to 1.0, and confidence intervals were set to 95%. An exact p-value less than or equal to 0.05 was considered significant.
(A) To find whether topologically defined lineage families (e.g., BA DPM) differ in their requirement for DE-cad function, the number of all clones belonging to a given family was divided by the number of all clones with abnormalities in that family; this provided the “family score”, which then was compared to the overall score (all clones added). Families that show a significant difference from the overall score are highlighted in red. In (B), family scores are compared to each. As in (A), all significant differences are highlighted in red.
Note: 5 BLP-family clones containing 1 abnormal clone are not shown in these tables.