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. Author manuscript; available in PMC: 2010 Aug 15.
Published in final edited form as: Dev Biol. 2009 Jun 8;332(2):371–382. doi: 10.1016/j.ydbio.2009.06.005

Table 1.

Statistical analysis of the frequency of abnormalities in DE-cad mutant clones.

A
All Clones DAL DAM BA BLA BLD DPL DPM CP MB BLV
Total clones 134 13 1 16 22 13 29 5 8 12 10
Abnormal clones 43 5 0 2 8 3 13 4 3 2 2
Percent of Total 32% 38% 0% 13% 36% 23% 45% 80% 38% 17% 20%
p-value n/a 0.210 0.681 0.066 0.175 0.209 0.072 0.041 0.277 0.154 0.221
B
DAL
DAM 0.643
BA 0.099 0.882
BLA 0.279 0.652 0.081
BLD 0.236 0.786 0.289 0.219
DPL 0.247 0.567 0.023 0.189 0.117
DPM 0.132 0.333 0.011 0.092 0.045 0.145
CP 0.354 0.667 0.158 0.328 0.295 0.295 0.163
MB 0.176 0.846 0.387 0.161 0.355 0.071 0.027 0.238
BLV 0.236 0.818 0.361 0.223 0.382 0.121 0.045 0.294 0.406
DAL DAM BA BLA BLD DPL DPM CP MB BLV

Calculations were carried out using “Simple Interactive Statistical Analysis” available at http://www.quantitativeskills.com/sisa/statistics/t-thlp.htm. Because the data set contained values close to or equal to 0, Fisher exact analysis was used for all comparisons. Design effects were set to 1.0, and confidence intervals were set to 95%. An exact p-value less than or equal to 0.05 was considered significant.

(A) To find whether topologically defined lineage families (e.g., BA DPM) differ in their requirement for DE-cad function, the number of all clones belonging to a given family was divided by the number of all clones with abnormalities in that family; this provided the “family score”, which then was compared to the overall score (all clones added). Families that show a significant difference from the overall score are highlighted in red. In (B), family scores are compared to each. As in (A), all significant differences are highlighted in red.

Note: 5 BLP-family clones containing 1 abnormal clone are not shown in these tables.