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. Author manuscript; available in PMC: 2011 Jan 1.

Published in final edited form as: Pharmacogenet Genomics. 2010 Jan;20(1):26–37. doi: 10.1097/FPC.0b013e3283343296

Fig 6 — Fitted velocity versus substrate concentration curves and Eadie-Hofstee plots for SMX-HA reduction in human liver microsomes heterozygous for the R59H (a), T117S (b), and R297H (c) CYB5R3 cSNPs.. Kinetic experiments were performed for individual livers with (□) R59H, (▼) T117S, and (○) R297H CYB5R3 allozymes. Data for the T117S livers was fit to the Michaelis-Menten equation (data from one representative liver shown), while the kinetic constants for the high and low-K_m components of the R59H and R297H livers were derived from Hanes plots.

Fig 6 — Fitted velocity versus substrate concentration curves and Eadie-Hofstee plots for SMX-HA reduction in human liver microsomes heterozygous for the R59H (a), T117S (b), and R297H (c) CYB5R3 cSNPs.. Kinetic experiments were performed for individual livers with (□) R59H, (▼) T117S, and (○) R297H CYB5R3 allozymes. Data for the T117S livers was fit to the Michaelis-Menten equation (data from one representative liver shown), while the kinetic constants for the high and low-K_m components of the R59H and R297H livers were derived from Hanes plots.