. Author manuscript; available in PMC: 2011 Mar 1.

Published in final edited form as: Hepatology. 2010 Mar;51(3):986–995. doi: 10.1002/hep.23411

Table II.

Changes in SAMe, MTA, SAH levels during in vivo HSC activation

Rat HSCs	SAMe	MTA	SAH	SAMe/SAH ratio
Sham	2.17 ± 0.36	0.32 ± 0.02	0.28 ± 0.09	8.99 ± 1.82
BDL	0.91 ± 0.13^*	0.21 ± 0.02^†	0.17 ± 0.04	5.85 ± 1.07

Rat HSCs were isolated from 10-day BDL livers or corresponding sham control livers as described in methods. SAMe, MTA and SAH levels were assessed by HPLC analysis of HSCs from each group. The unit for these metabolites is nmol/mg protein. The results represent Mean±S.E from four HSC preparations;

p<0.05,

^†

p<0.005 vs. sham control.