Fig. 2. JFH1 core RNA sequence does not decrease H77pp yield.
The core gene region in the H77 E1E2 expression vector was replaced with the entire JFH1 core gene (191aa) or with that encoding the C-terminal 20aa. HCVpp were generated and tested as in Fig 1A. Solid bar: homologous core; hatched bar: heterologous core.