Table 3.
Multivariate adjusted hazard ratiosa for all-cause mortalityb among race/ethnicities using Cox proportional hazards model.
| Race/Ethnicity | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Non-Hispanic White | Non-Hispanic Black | Hispanic/Latino | Asian/Pacific Islander | |||||||||
| Characteristic | N | HR | 95% CI | N | HR | 95% CI | N | HR | 95% CI | N | HR | 95% CI |
| Sex | ||||||||||||
| Males | 1,178 | 1.00† (Ref) | — | 169 | 1.00† (Ref) | — | 701 | 1.00† (Ref) | — | 209 | 1.00† (Ref) | — |
| Females | 627 | 0.66 | 0.54–0.82 | 92 | 0.77 | 0.48–1.23 | 364 | 0.54 | 0.42–0.70 | 149 | 0.73 | 0.45–1.20 |
| Age at Diagnosis | ||||||||||||
| By year | 1,805 | 1.02 | 1.01–1.04 | 261 | 1.01 | 0.97–1.04 | 1,065 | 1.02* | 1.01–1.04 | 358 | 1.02 | 0.99–1.05 |
| Tumor Stage | ||||||||||||
| Local | 538 | 1.00† (Ref) | — | 68 | 1.00† (Ref) | — | 341 | 1.00† (Ref) | — | 139 | 1.00† (Ref) | — |
| Regional | 367 | 1.21 | 0.86–1.71 | 47 | 0.80 | 0.36–1.79 | 202 | 1.46 | 0.99–2.16 | 88 | 1.01 | 0.47–2.19 |
| Distant | 900 | 3.41* | 2.60–4.47 | 146 | 1.89* | 1.02–3.49 | 522 | 3.16* | 2.28–4.39 | 131 | 3.08* | 1.65–5.77 |
| Nodality | ||||||||||||
| Nodal | 1,319 | 1.00 (Ref) | — | 180 | 1.00 (Ref) | — | 691 | 1.00 (Ref) | — | 216 | 1.00 (Ref) | — |
| Extranodal | 486 | 1.51* | 1.21–1.87 | 81 | 0.66 | 0.37–1.16 | 374 | 1.14 | 0.88–1.47 | 142 | 1.43 | 0.85–2.40 |
| First-course Chemotherapy | ||||||||||||
| Yes | 1,513 | 1.00 (Ref) | — | 222 | 1.00 (Ref) | — | 915 | 1.00 (Ref) | — | 295 | 1.00 (Ref) | — |
| No | 292 | 1.24 | 0.90–1.71 | 39 | 2.02* | 1.09–3.71 | 150 | 1.71* | 1.19–2.46 | 63 | 0.25* | 0.08–0.74 |
| First-course Radiation | ||||||||||||
| Yes | 644 | 1.00 (Ref) | — | 86 | 1.00 (Ref) | — | 309 | 1.00 (Ref) | — | 155 | 1.00 (Ref) | — |
| No | 1,161 | 0.90 | 0.74–1.11 | 175 | 0.80 | 0.50–1.29 | 756 | 0.98 | 0.76–1.27 | 203 | 126 | 0.77–2.07 |
| nSES | ||||||||||||
| Highest | 517 | 1.00 (Ref)† | — | 18 | 1.00 (Ref) | — | 88 | 1.00 (Ref) | — | 125 | 1.00 (Ref) | — |
| High | 454 | 1.19 | 0.91–1.55 | 43 | 0.86 | 0.33–2.24 | 138 | 1.14 | 0.69–1.88 | 87 | 0.54 | 0.25–1.17 |
| Middle | 388 | 1.33* | 1.01–1.75 | 60 | 0.63 | 0.24–1.65 | 188 | 0.94 | 0.59–1.50 | 69 | 0.90 | 0.46–1.74 |
| Low | 287 | 1.62* | 1.22–2.14 | 71 | 0.68 | 0.27–1.71 | 273 | 1.06 | 0.68–1.64 | 40 | 1.06 | 0.51–2.24 |
| Lowest | 159 | 2.25* | 1.64–3.08 | 69 | 0.51 | 0.20–1.33 | 378 | 0.97 | 0.63–1.50 | 37 | 1.17 | 0.59–2.33 |
| Insurance | ||||||||||||
| None | 61 | 1.00 (Ref) | — | 12 | 1.00 (Ref) | — | 93 | 1.00 (Ref) | — | 14 | 1.00 (Ref) | — |
| Managed or Private | 1,290 | 0.87 | 0.54–1.38 | 144 | 1.65 | 0.38–7.11 | 508 | 0.64* | 0.43–0.95 | 267 | 0.91 | 0.31–2.71 |
| Government | 317 | 1.27 | 0.78–2.05 | 78 | 5.97* | 1.41–25.24 | 340 | 1.00 | 0.68–1.47 | 53 | 1.47 | 0.48–4.56 |
| Unknown | 137 | 0.80* | 0.45–1.40 | 27 | 1.72 | 0.35–8.48 | 124 | 0.98 | 0.62–1.53 | 24 | 0.80 | 0.17–3.78 |
Source: California Cancer Registry. Individuals diagnosed between January 1, 1996–December 31, 2005. Abbreviations: nSES: neighborhood socioeconomic status, HR: hazard ratio, CI: confidence interval, Ref: reference.
aAll adjusted hazard ratios are fully adjusted for the other variables in the model, in addition to gender, major histology (Burkitt's, follicular, lymphoblastic, diffuse large B-cell, anaplastic, and other/unknown) and diagnostic year. Results for individuals with race/ethnicity other than what is listed (N = 40), or cases missing data for stage (N = 202) or chemotherapy (N = 42) were excluded from analysis.
*Test for significance at α = 0.05.
†Test for trend significant at α = 0.05.