Figure 2 ¹¹C-PiB mean cortical binding potential (MCBP) for unimpaired HIV+ participants and community controls

(A) A 2 × 2 matrix is created using CSF Αβ42 (<500 pg/mL) and MCBP (>0.18 arbitrary units). All HIV+ participants had normal ¹¹C-PiB (<0.18 arbitrary units) regardless of their CSF Αβ42. In contrast, half (3/6) of the community controls with reduced CSF Αβ42 (<500 pg/mL) had elevated MCBP (>0.18 arbitrary units). (B) Regional cortical binding potentials were determined for HIV+ participants and community controls with low (<500 pg/mL) and normal CSF Αβ42 (≥500 pg/mL). Community controls with low CSF Αβ42 (<500 pg/mL) had elevated binding potentials (>0.18 arbitrary units) compared to other groups (*p < 0.01).