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Gel-shift analysis of the transcripton factor NFκ B. Treatment with Rhizoma coptidis inhibited binding activity in a dose-dependent (incubation time 240 min), (a) and time-dependent (dilution 1 : 5), (b) fashion. NFκ B: nuclear factorκ B, Co: LPS-stimulated control cells, and CC: cold competition. *P < .005, **P < .001.
