Table 1.
Modulation of gene expression by hypoxia in neuroblastoma cell lines.
| cell line | gene expression(1) | |||
|---|---|---|---|---|
| name | Morphology(2) | MYCN amplification(3) | up-regulated | down-regulated |
| ACN | neuroblast (N) | − | 1400 | 1317 |
| SHEP-2 | epithelial (S) | − | 1609 | 1043 |
| GI-ME-N | neuroblast (N) | − | 762 | 881 |
| SK-N-F1 | epithelial (S) | − | 1206 | 1051 |
| SK-N-SH | neuroblast/epithelial (I) | − | 922 | 758 |
| SK-N-BE(2)c | neuroblast/epithelial (I) | + | 855 | 1273 |
| IMR-32 | neuroblast (N) | + | 1000 | 1077 |
| LAN-1 | neuroblast (N) | + | 1061 | 1016 |
| GI-LI-N | neuroblast (N) | + | 1516 | 1002 |