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. Author manuscript; available in PMC: 2011 May 1.
Published in final edited form as: Pediatr Res. 2010 May;67(5):532–537. doi: 10.1203/PDR.0b013e3181d4ff4d

Figure 3. Phenobarbital potentiates hypothermic neuroprotection: late outcome.

Figure 3

Injury severity was scored (0–4) in 7 brain regions, with substantial variation in scores in both groups. Total scores, providing an overall measure of damage severity, were lower in the phenobarbital-treated group (PB+dHT) (p<0.05, Mann-Whitney, panel A). Panel B includes scores in each region; anterior cortex at the level of striatum, posterior cortex at the level of hippocampus, striatum, thalamus, and hippocampal CA1, CA3 and dentate gyrus (DG). Data in box plots are: median (horizontal bar), IQR (25th–75th percentile, box) and range (whiskers). Regional scores were significantly lower in the PB+dHT group in striatum, thalamus and hippocampus CA3 (Mann-Whitney, p <0.05).