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. Author manuscript; available in PMC: 2011 May 1.
Published in final edited form as: Curr Oncol Rep. 2010 May;12(3):193–201. doi: 10.1007/s11912-010-0093-4

Table 2.

Clinical features from RCC nomograms predictive for recurrence or survival

Marker Nomogram Year n Histology Stages
Patient characteristics
        Bone/liver metastases Mayo [53] 2005 727 Clear cell Metastatic
        Hemoglobin MSKCC [51] 1999 670 All Metastatic
        Multiple metastases Mayo [53] 2005 727 Clear cell Metastatic
        Nephrectomy MSKCC [51] 1999 670 All Metastatic
        Presence of hepatic/pulmonary/lymph node metastases Cleveland Clinic [52] 2005 353 All Metastatic
        Prior radiotherapy Cleveland Clinic [52] 2005 353 All Metastatic
        Resection of metastases Mayo [53] 2005 727 Clear cell Metastatic
        Serum calcium MSKCC [51] 1999 670 All Metastatic
Cleveland Clinic [52] 2005 353 All Metastatic
        Serum LDH MSKCC [51] 1999 670 All Metastatic
Cleveland Clinic [52] 2005 353 All Metastatic
        Symptoms/performance status MSKCC [51] 1999 670 All Metastatic
MSKCC [48] 2001 601 All Localized
UISS [47] 2001 661 All All
Mayo [53] 2005 727 Clear cell Metastatic
MSKCC [50] 2005 701 Clear cell Localized
        Time to progression Mayo [53] 2005 727 Clear cell Metastatic
        Time to study entry Cleveland Clinic [52] 2005 353 All Metastatic
Tumor characteristics
        Grade UISS [47] 2001 661 All All
SSIGN [49] 2002 1801 Clear cell All
Mayo [53] 2005 727 Clear cell Metastatic
MSKCC [50] 2005 701 Clear cell Localized
        Histology MSKCC [48] 2001 601 All Localized
        Microvascular invasion MSKCC [50] 2005 701 Clear cell Localized
        TNM stage AJCC [56] 2005 1065 All Localized
MSKCC [48] 2001 601 All Localized
UISS [47] 2001 661 All All
SSIGN [49] 2002 1801 Clear cell All
MSKCC [50] 2005 701 Clear cell Localized
        Tumor necrosis SSIGN [49] 2002 1801 Clear cell All
Mayo [53] 2005 727 Clear cell Metastatic
MSKCC [50] 2005 701 Clear cell Localized
        Tumor size MSKCC [48] 2001 601 All Localized
SSIGN [49] 2002 1801 Clear cell All
MSKCC [50] 2005 701 Clear cell Localized
        Tumor thrombus Mayo [53] 2005 727 Clear cell Metastatic

AJCC—American Joint Committee on Cancer; LDH—lactate dehydrogenase; MSKCC—Memorial Sloan-Kettering Cancer Center; RCC—renal cell carcinoma; SSIGN—Stage, Size, Grade, and Necrosis; TNM—tumor node metastasis; UISS—UCLA integrated scoring system.