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. Author manuscript; available in PMC: 2010 Jul 19.
Published in final edited form as: Invest Ophthalmol Vis Sci. 2009 Jul 15;50(12):5630–5638. doi: 10.1167/iovs.09-3791

FIGURE 4.

FIGURE 4

Schematic description of nuclear protein gene patterns that may affect proliferation of SP cells. Overexpression of multiple nuclear dual specificity phosphatases may simultaneously decrease proliferative and migratory responses to growth factors in the SP cells. Large overexpression of MXD1 will add to the blockade of growth factors responses by sequestering MAX, the cofactor for MYC. Overexpression of the cyclin D kinase inhibitors and simultaneous under-expression of cyclin D and its dependent kinases could also have similar effects.