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. Author manuscript; available in PMC: 2010 Jul 19.
Published in final edited form as: Wiley Interdiscip Rev Syst Biol Med. 2009;1(1):141–149. doi: 10.1002/wsbm.28

Table 1.

Spatial reorganization and timescales of various signaling components following a stimulus from a pipette

Molecule Activation time scale Asymmetry
G protein <1 s None
Ras 3 s Front/back
PH-domain proteins 5 s Front/back
PI3K 15 s Front/back
PTEN 10 s Back/front
Actin 5 s Front/back
PAKa 30 s Back/front
MyoII 30 s Back/front