Model for the respiratory chain of D. vulgaris during growth on hydrogen, or lactate, and sulfate. The model is based on previous observations (for review, see Refs. 13 and 28) and the present results as discussed in the text under (“Discussion”). Ldh, lactate dehydrogenase; Por, pyruvate:ferredoxin oxidoreductase; Pta, phosphate acetyltransferase; Ack, acetate kinase; Fd, ferredoxin; Ech and Coo, membrane-bound cytoplasmic-facing hydrogenases; Hyn1, [NiFe] hydrogenase isozyme 1; Hyd, [FeFe] hydrogenase; Hys, Pfl, pyruvate-formate lyase; Sat, sulfate adenylyl transferase; APS, adenosine phoshosulfate[NiFeSe] hydrogenase; Ohc, octaheme cytochrome complex; ATPS, ATP synthase; MQ, menaquinone; MQH2, menaquinol.