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Proposed mechanism of EfP-I action involving both induced fit and lock and key models. A, EfP-I reacting with the same chromogenic substrate: first by induced fit and subsequently by lock and key. B, EfP-I reacting sequentially with CU, CTH, and CU, undergoing induced fit and then lock and key. C, EfP-I reacting sequentially with CTH, CU, and CTH, undergoing induced fit and then lock and key.
