FIGURE 2.
A, PcrH(21–160) displays a 7-helical TPR-like fold. Each one of the TPR domains is shown in a different color, with helix 7 in violet. B, superposition of IpgC (orange), SycD (pink), and PcrH (cyan) reveals very similar overall folds, with differences mostly at the N termini. C, PcrH displays a highly charged surface. Indicated residues point directly into the concave cleft and interact with the partner molecule. D, dimer interactions are made through the convex side of the TPR fold of PcrH.