TABLE 2.
Serum chemistries in transplanted animals
Data are presented as mean ± S.E. for ≥9 animals per genotype. FFA, free fatty acid.
| Donor | LXRα+/+ FASKOM apoE−/− |
LXRα−/− FASKOM apoE−/− |
||||
|---|---|---|---|---|---|---|
| Base line | 4 weeks | 8 weeks | Base line | 4 weeks | 8 weeks | |
| Cholesterol (mg/dl) | 405 ± 71 | 1596 ± 54a | 1469 ± 43a | 353 ± 44 | 1460 ± 129a | 1382 ± 48a |
| Triglycerides (mg/dl) | 214 ± 23 | 191 ± 21 | 128 ± 10a | 171 ± 31 | 202 ± 39 | 174 ± 20 |
| FFA (mg/dl) | 1.68 ± 0.03 | 1.82 ± 0.13 | 2.15 ± 0.15a | 1.20 ± 0.13 | 1.99 ± 0.23a | 2.79 ± 0.15a |
| Glucose (mg/dl) | 189 ± 12 | 315 ± 21a | 185 ± 11 | 170 ± 7 | 306 ± 29a | 175 ± 23 |
a p < 0.05 compared with base line.