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Integrin CR3 (CD11b/CD18) promotes invasion of Factor H-coated pneumococci into epithelial cells. Invasion and intracellular survival of pneumococci in CHO-WT (CHO-K1 cells) and CHO-CR3 cells were determined by the antibiotic protection assay. The results are shown relative to infections conducted with untreated pneumococci. *, p < 0.05; **, p < 0.01; ns, not significant.
