Table 1.
CD patients vs Controls (PC1) | ||||
---|---|---|---|---|
TTGE band § | Active + Inactive (%) | Control (%) | VIP | P value (a) |
26 (E.coli) | 92.1 | 20.0 | 2.023 | < 0.0001 |
18 (P.distasonis) | 86.8 | 20.0 | 1.867 | < 0.0001 |
39 (P.distasonis) | 89.5 | 20.0 | 1.847 | 0.0001 |
35 | 73.7 | 0.0 | 1.802 | < 0.0001 |
1 (B.vulgatus) | 89.5 | 20.0 | 1.755 | 0.001 |
13 | 57.9 | 0.0 | 1.580 | 0.000 |
15 | 63.2 | 0.0 | 1.535 | 0.001 |
29 | 60.5 | 0.0 | 1.516 | 0.001 |
3 | 52.6 | 0.0 | 1.311 | 0.003 |
6 | 60.5 | 0.0 | 1.194 | 0.010 |
22 | 52.6 | 10.0 | 1.151 | 0.007 |
16 | 39.5 | 0.0 | 1.024 | 0.018 |
Active CD patients vs Inactive CD patients (PC2) | ||||
TTGE band§ | Active(%) | Inactive(%) | VIP | P value(b) |
8 (P.distasonis) | 31.6 | 0.0 | 1.691 | 0.009 |
1 (B.vulgatus) | 84.2 | 94.7 | 1.687 | 0.026 |
6 | 47.4 | 73.7 | 1.667 | 0.089 |
7 | 26.3 | 0.0 | 1.522 | 0.015 |
21 | 21.1 | 0.0 | 1.507 | 0.023 |
26 | 94.7 | 89.5 | 1.498 | 0.474 |
39 | 89.5 | 89.5 | 1.475 | 1.000 |
13 | 73.7 | 42.1 | 1.316 | 0.054 |
18 | 94.7 | 78.9 | 1.299 | 0.032 |
35 | 78.9 | 68.4 | 1.271 | 0.255 |
12 | 36.8 | 10.5 | 1.258 | 0.049 |
15 | 68.4 | 57.9 | 1.079 | 0.386 |
5 | 36.8 | 15.8 | 1.056 | 0.083 |
29 | 68.4 | 52.6 | 1.054 | 0.237 |
19 | 47.4 | 63.2 | 1.046 | 0.237 |
9 | 78.9 | 94.7 | 1.031 | 0.255 |
§ Bands were self numbered according to the order of appearance (top-bottom) on the TTGE gel and are listed in descending order of importance (VIP) in the PLS-DA model. Between parentheses are reported the species used in the gel marker that run parallel to specific TTGE bands.
(a) Mann-Whitney U-test, α = 0.05
(b) Wilcoxon signed rank test, α = 0.05