Table 5.
Sensitivities and specificities of CareStart™ Malaria HRP-2/pLDH (Pf/pan) Combo Test for the detection of P. falciparum
| Results of microscopy corrected by PCR | Numbers | Identified as P. falciparum by CareStart™ Malaria HRP-2/pLDH (Pf/pan) Combo Test | % Sensitivity (95% C.I.) | % Specificity (95% C.I.) |
|---|---|---|---|---|
| All P. falciparum samples | 320 | 284 | 88.8 (84.8-92.0) | |
| Pure gametocytaemia | 17 | 12 | 70.6 (44.0-89.7) | |
| Asexual parasite density 0-100/μl | 56 | 39 | 69.6 (55.9-81.2) | |
| Asexual parasite density 101-200/μl | 35 | 29 | 82.9 (66.4-93.4) | |
| Asexual parasite density 201-1,000/μl | 79 | 72 | 91.1 (82.6-96.4) | |
| Asexual parasite density > 1,000/μl | 133 | 132 | 99.3 (95.9-100) | |
| Asexual parasite density > 100/μl | 247 | 233 | 94.3 (90.7-96.9) | |
| All other species and no parasites seen | 270 | 3 | 98.9 (96.8-99.8) | |
| No parasites seen | 95 | 0 | 100.0 (96.2-100) | |
| P. vivax | 76 | 2 | ||
| P. ovale | 76 | 1 | ||
| P. malariae | 23 | 0 |