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. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: J Gene Med. 2010 Jul;12(7):572–579. doi: 10.1002/jgm.1469

Figure 1.

Figure 1

The structural map of the recombinant adenovirus; both antitumor effect and bio-luminescence imaging were obtained in the same set of animals utilizing this construct. I: Human Ad5 sequence (wt 1–458; includes 5’ L-ITR and packaging signal). II: CMV-HSV tK Poly A-CMV-Luc-PolyA. III: Human Ad5 sequences (wt 351335935; E3 region deleted, includes 3’ R-ITR), E3 deletion: 28587–30464.