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. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: J Gene Med. 2010 Jul;12(7):572–579. doi: 10.1002/jgm.1469

Figure 2.

Figure 2

Antitumor efficacy of adenoviruses injected intratumorally in nude mice in conjunction with intraperitoneal GCV. Each data point shows the mean tumor volume of the group with the standard error. A) Therapeutic adenovirus doses (Ad-Luc-Tk) V1 = 1×108 PFU and V2 = 2×108 PFU, were injected alone or in 4 wt % SELP-47K or SELP-815K polymers, *P < 0.05 compared to control group (normal saline). B) Subset of data from 2A to show differences in antitumor effect between animals injected with 2×108 PFU Ad-Luc-Tk in SELP (-47K, and -815K with GCV) to 2×108 PFU Ad-Tk-Luc (V2-GCV) injected in saline, *P < 0.05 compared to V2.