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. Author manuscript; available in PMC: 2011 Aug 15.

Published in final edited form as: Clin Infect Dis. 2010 Aug 15;51(4):392–400. doi: 10.1086/655130

Rate of accrual of life years in the HIV-infected population (vertical axis) with a transmissible HIV RNA (>500 copies/ml) over a ten-year time horizon (horizontal axis). The height of the curve denotes the number of people with transmissible viral load living in the population at any moment in time. The area under each curve represents the community viral load burden. Five representative strategies are shown: no regular screen, no ART strategy (clear); current practice (black); annual testing, ART at ≤350/μl (gray); test and treat (hatched); and test and treat with optimized ART (dotted). Figures a-c represent each of these strategies under alternative assumptions about the participation index: base case, 9.4% (2a), optimistic, 38% (2b), and idealized, 73% (2c).

Rate of accrual of life years in the HIV-infected population (vertical axis) with a transmissible HIV RNA (>500 copies/ml) over a ten-year time horizon (horizontal axis). The height of the curve denotes the number of people with transmissible viral load living in the population at any moment in time. The area under each curve represents the community viral load burden. Five representative strategies are shown: no regular screen, no ART strategy (clear); current practice (black); annual testing, ART at ≤350/μl (gray); test and treat (hatched); and test and treat with optimized ART (dotted). Figures a-c represent each of these strategies under alternative assumptions about the participation index: base case, 9.4% (2a), optimistic, 38% (2b), and idealized, 73% (2c).