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. Author manuscript; available in PMC: 2011 Sep 1.
Published in final edited form as: Int J Radiat Oncol Biol Phys. 2010 Apr 13;78(1):297–305. doi: 10.1016/j.ijrobp.2009.11.008

Figure 4.

Figure 4

Treatment of a murine spontaneous lung tumor with the microCT radiotherapy system. A-C: A MYC-induced tumor growing in the base of the right lung of a mouse was imaged with microCT, shown in axial, coronal, and sagittal sections with the tumor volume outlined in red. D: A treatment consisting of 8 beams of diameter 8 mm at isocenter with angular spacing of 45° was constructed in RT_Image to irradiate the target (red) to a dose of 2 Gy. E: Monte Carlo simulation of the dose delivered by this plan, with the 1, 1.4, and 1.8 Gy isodose contours shown in green, yellow, and red, respectively. F: γH2AX (green) and DAPI immunohistochemical sections from the target tumor. G: Corresponding immunohistochemical sections from the left lung that received an average dose of 0.3 Gy.