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Outcome of Oral Methotrexate Therapy (12.5 mg orally/week) in a Prospective, Randomized Trial (Ref. 16)
| Placebo n=37 |
Methotrexate n=30 |
|
|---|---|---|
| Remission (n) | 48.6% (18) | 46.7% (14) |
| Time to remission (months) | 3.4 ± 1.7 | 4.1 ± 1.9 |
| Relapse after achieving remission (n) |
44.4% (8) | 46.7% (9) |
| Drop outs (n) | 24.3% (9) | 6.7% (2) |
| Treatment failure | 5.4% (2) | 10% (3) |
| Withdrawal because of side effect | 2.7% (1) | 6.7% (2) |
