Figure 1.
Western immunoblot of the polyclonal LRRK2 antiserum PA0362 (Novus Biologicals-NB110-58771SS) showing that these Lrrk2 antibodies detect a single band that corresponds to the molecular weight (approximately 280kd) of Lrrk2 protein when run against hWT TG (BAC mice expressing human wild type Lrrk2) and murine Lrrk2 in NT (non-transgenic control), but do not detect any band labeling when applied on LKO (LRRK2 Knockout mouse) brain tissue.